GeneralBiochemistry

Serum Osmolal Gap

Difference between measured and calculated osmolality. Gap > 10 mOsm/kg suggests toxic alcohols, ketones, or renal failure.

Measured serum osmolality (from lab)

mOsm/kg

Sodium

mmol/L

Glucose

mmol/L

Urea

mmol/L

Reference: UK formula: 2[Na] + [glucose] + [urea] (all in mmol/L)

Medical Disclaimer: This calculator is a clinical decision support tool for qualified healthcare professionals. It does not replace clinical judgement. Always interpret results in the full clinical context. Reference: UK formula: 2[Na] + [glucose] + [urea] (all in mmol/L).

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