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👤 Adult👶 Paediatric

Zidovudine

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

24 known interactions (2 severe)
2 brand names

Indications

  • HIV infection in combination with other antiretroviral drugs
  • Prevention of maternal-fetal HIV transmission
  • HIV infection in combination with other antiretroviral drugs in patients temporarily unable to take zidovudine by mouth

Drug Interactions

2 SevereModerate interactionsMinor interactions

24 drug interactions identified for Zidovudine. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Elderly; lactic acidosis; risk of haematological toxicity particularly with high dose and advanced disease; vitamin B 12 deficiency (increased risk of neutropenia) Cautions, further information Lactic

Side Effects

Commonneut

Full side effect profile available in the MedNext app.

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Zidovir(IN)Retrovir(IN, PK, SA, AE, EG, ZA, NG)
Mn

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In the MedNext App

  • Complete dosing regimens
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  • All 2 brand names
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  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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