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👤 Adult

Tadalafil

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

40 known interactions (5 severe)
4 brand names

Indications

  • Pulmonary arterial hypertension (initiated under specialist supervision)
  • Erectile dysfunction
  • Erectile dysfunction;

+ 1 more indication in the full monograph

Drug Interactions

5 SevereModerate interactions

40 drug interactions identified for Tadalafil. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

When used for Benign prostatic hyperplasia Anatomical deformation of the penis (e.g. angulation, cavernosal fibrosis, Peyronie’s disease); cardiovascular disease; left ventricular outflow obstruction;

Side Effects

Commonrefl
Uncommonrefl

Full side effect profile available in the MedNext app.

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Cialis(IN, PK, SA, AE, EG, ZA, NG)Megalis(IN)+ 2 more in app
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 4 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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