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👤 Adult

Siltuximab

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

5 known interactions
1 brand name

Indications

  • Treatment of multicentric Castleman's disease (MCD) in patients who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative

Drug Interactions

Moderate interactions

5 drug interactions identified for Siltuximab. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫁Hepatic impairment guidance

Cautions

Patients at increased risk of gastrointestinal perforation—promptly investigate those presenting with symptoms suggestive of gastrointestinal perforation; severe infection—withhold treatment until res

Side Effects

Commonincreas

Full side effect profile available in the MedNext app.

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Sylvant(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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