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👤 Adult👶 Paediatric

Posaconazole

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

68 known interactions (4 severe)
1 brand name

Indications

  • Invasive aspergillosis
  • Invasive aspergillosis either refractory to, or in patients intolerant of, itraconazole or amphotericin B, Fusariosis either refractory to, or in patients intolerant of, amphotericin B, Chromoblastomycosis and mycetoma either refractory to, or in patients intolerant of, itraconazole, Coccidioidomycosis either refractory to, or in patients intolerant of, amphotericin B, itraconazole, or fluconazole
  • Oropharyngeal candidiasis (severe infection or in immunocompromised patients only)

+ 1 more indication in the full monograph

Drug Interactions

4 SevereModerate interactions

68 drug interactions identified for Posaconazole. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Administration by intravenous infusion, particularly by peripheral catheter (increased risk of QTc interval prolongation); body-weight over 120 kg (risk of treatment failure possibly increased); body-

Side Effects

Common or very common Appetite decreased; asthenia; constipation; diarrhoea; dizziness; drowsiness; dry mouth; electrolyte imbalance; fever; gastroint...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Noxafil(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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