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👤 Adult

Pirfenidone

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

18 known interactions (1 severe)
2 brand names

Indications

  • Treatment of mild to moderate idiopathic pulmonary fibrosis (initiated under specialist supervision)

Drug Interactions

1 SevereModerate interactionsMinor interactions

18 drug interactions identified for Pirfenidone. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Cautions, further information Photosensitivity Manufacturer advises avoid exposure to direct sunlight—if photosensitivity reaction or rash occurs, dose adjustment or treatment interruption may be requ

Side Effects

Common or very common Appetite decreased; arthralgia; asthenia; constipation; diarrhoea; dizziness; drowsiness; gastrointestinal discomfort; gastroint...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Pirfenex(IN)Esbriet(IN, PK, SA, AE, EG, ZA, NG)
Mn

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In the MedNext App

  • Complete dosing regimens
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  • All 2 brand names
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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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