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👤 Adult👶 Paediatric

Phenytoin

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

29 known interactions (1 severe)
3 brand names

Indications

  • Tonic-clonic seizures , Focal seizures
  • Tonic-clonic seizures , Focal seizures, Prevention and treatment of seizures during or following neurosurgery or severe head injury
  • Prevention and treatment of seizures during or following neurosurgery or severe head injury

+ 1 more indication in the full monograph

Drug Interactions

1 SevereModerate interactions

29 drug interactions identified for Phenytoin. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫁Hepatic impairment guidance

Cautions

General cautions: Enteral feeding (interrupt feeding for 2 hours before and after dose; more frequent monitoring may be necessary); presence of HLA-B*1502 allele; seizures (may be exacerbated) Specifi

Side Effects

General side-effects: Frequency not known Agranulocytosis; bone disorders; bone fracture; bone marrow disorders; cerebrovascular insufficiency; coarse...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Eptoin(IN)Dilantin(IN)+ 1 more in app
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 3 brand names
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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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