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Methylnaltrexone Bromide

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

3 known interactions
1 brand name

Indications

  • Opioid-induced constipation in patients with chronic pain (except palliative care patients with advanced illness)
  • Adjunct to other laxatives in opioid-induced constipation in palliative care

Drug Interactions

Moderate interactions

3 drug interactions identified for Methylnaltrexone Bromide. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

bromide Diverticular disease (when active); faecal impaction; gastro-intestinal tract lesions (known or suspected); patients with colostomy; patients with peritoneal catheter

Side Effects

bromide Common or very common Abdominal pain; diarrhoea; dizziness; gastrointestinal disorders; nausea; opioid withdrawal-like syndrome; vomiting Over...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Relistor(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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