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👤 Adult👶 Paediatric

Melatonin

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

5 known interactions
2 brand names

Indications

  • Insomnia [short-term use]
  • Jet lag [short-term use]
  • Insomnia in patients with learning disabilities and behaviour that challenges [where sleep hygiene measures have been insufficient] (initiated under specialist supervision)

Drug Interactions

Moderate interactions

5 drug interactions identified for Melatonin. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Autoimmune disease; susceptibility to seizures (risk of increased seizure frequency) Cautions, further information Autoimmune disease Avoid—limited information available in patients with autoimmune di

Side Effects

Commonhyperbilirubinaemi
Uncommonhyperbilirubinaemi

Full side effect profile available in the MedNext app.

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Meloset(IN)Circadin(IN, PK, SA, AE, EG, ZA, NG)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 2 brand names
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  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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