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👤 Adult👶 Paediatric

Lumacaftor With Ivacaftor

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

1 brand name

Indications

  • Cystic fibrosis (specialist use only)

Safety Information

🫁Hepatic impairment guidance

Cautions

with ivacaftor Forced expiratory volume in 1 second (FEV 1 ) less than 40% of the predicted normal value—additional monitoring recommended at initiation of treatment; pulmonary exacerbation—no informa

Side Effects

Commoncyc

Full side effect profile available in the MedNext app.

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Orkambi(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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