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👤 Adult👶 Paediatric

Ketoconazole

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

484 known interactions (24 severe)
3 brand names

Indications

  • Endogenous Cushing's syndrome (specialist use only)
  • Tinea pedis
  • Fungal skin infection (not Tinea pedis)

+ 2 more indications in the full monograph

Drug Interactions

24 SevereModerate interactionsMinor interactions

484 drug interactions identified for Ketoconazole. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫁Hepatic impairment guidance

Cautions

With oral use Pre-treatment liver enzymes should not exceed 2 times the normal upper limit; risk of adrenal insufficiency With topical use Avoid contact with eyes; avoid contact with mucous membranes

Side Effects

CommonCommon or very common With oral use Adrenal insufficienc
UncommonCommon or very common With oral use Adrenal insufficienc
RareCommon or very common With oral use Adrenal insufficienc

Full side effect profile available in the MedNext app.

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Nizral(IN)Ketovate(IN)+ 1 more in app
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 3 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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