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👤 Adult👶 Paediatric

Isotretinoin

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

2 known interactions
4 brand names

Indications

  • Severe acne [(such as nodular or conglobate acne or acne at risk of permanent scarring) resistant to adequate courses of standard therapy with systemic antibacterials and topical therapy] (under expert supervision)

Drug Interactions

Moderate interactions

2 drug interactions identified for Isotretinoin. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Important safety information For isotretinoin MHRA/CHM advice: Isotretinoin ( Roaccutane ®): rare reports of erectile dysfunction and decreased libido (October 2017) An EU-wide review has concluded th

Side Effects

Commonpro

Full side effect profile available in the MedNext app.

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Isotroin(IN)Tretiva(IN)+ 2 more in app
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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