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👤 Adult

Hydrochlorothiazide

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

37 known interactions (3 severe)
5 brand names

Indications

  • Indications listed in combination monographs (available in the UK only in combination with other drugs)

Drug Interactions

3 SevereModerate interactions

37 drug interactions identified for Hydrochlorothiazide. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

thiazides and related diuretics Diabetes; gout; risk of hypokalaemia; systemic lupus erythematosus Cautions, further information Existing conditions Thiazides and related diuretics can exacerbate diab

Side Effects

Commonhype

Full side effect profile available in the MedNext app.

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Aquazide(IN)Hydrazide(IN)+ 3 more in app
Mn

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In the MedNext App

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

Related drugs

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Abacavir With Lamivudine

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Abacavir With Lamivudine And Zidovudine

Not classified · 0 interactions

Abaloparatide

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Abatacept

Not classified · 13 interactions

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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