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👤 Adult👶 Paediatric

Chloral Hydrate

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

5 known interactions
2 brand names

Indications

  • Severe insomnia [short-term use when insomnia is interfering with daily life and other therapies have failed]
  • Severe insomnia, using cloral betaine 707 mg (≡ 414 mg chloral hydrate) tablets [short-term use when insomnia is interfering with daily life and other therapies have failed]

Drug Interactions

Moderate interactions

5 drug interactions identified for Chloral Hydrate. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

hydrate Avoid contact with mucous membranes; avoid contact with skin; avoid prolonged use (and abrupt withdrawal thereafter); reduce dose in frail elderly

Side Effects

hydrate Frequency not known Agitation; allergic dermatitis; ataxia; confusion; delirium (more common on abrupt discontinuation); drug use disorders; g...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Chloral Hydrate(IN, PK, SA, AE, EG, NG)Welldorm(ZA)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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