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👤 Adult👶 Paediatric

Bupivacaine Hydrochloride

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

14 known interactions (1 severe)
2 brand names

Indications

  • Surgical anaesthesia, lumbar epidural block
  • Surgical anaesthesia, field block
  • Surgical anaesthesia, thoracic epidural block

+ 2 more indications in the full monograph

Drug Interactions

1 SevereModerate interactions

14 drug interactions identified for Bupivacaine Hydrochloride. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

hydrochloride Cardiovascular disease; cerebral atheroma; complete heart block; debilitated patients (consider dose reduction); elderly (consider dose reduction); epilepsy; hypertension; hypotension; h

Side Effects

Commoncardiac
Uncommoncardiac
Rarecardiac

Full side effect profile available in the MedNext app.

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Marcaine(IN, PK, SA, AE, EG, ZA, NG)Sensorcaine(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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