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👤 Adult👶 Paediatric

Baclofen

Clinically reviewed by MedNext Clinical Team. Last reviewed 1 January 2026. See our editorial policy and correction policy.

9 known interactions (1 severe)
2 brand names

Indications

  • Pain of muscle spasm in palliative care
  • Hiccup due to gastric distension in palliative care
  • Chronic severe spasticity resulting from disorders such as multiple sclerosis or traumatic partial section of spinal cord

+ 1 more indication in the full monograph

Drug Interactions

1 SevereModerate interactions

9 drug interactions identified for Baclofen. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

General cautions: Cerebrovascular disease; diabetes; elderly; epilepsy; history of peptic ulcer; history of substance abuse; hypertonic bladder sphincter; Parkinson’s disease; psychiatric illness; res

Side Effects

Severe chronic spasticity unresponsive to oral antispastic drugs (or where side-effects of oral therapy unacceptable) or as alternative to ablative ne...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Liofen(IN)Lioresal(IN, PK, SA, AE, EG, ZA, NG)
Mn

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In the MedNext App

  • Complete dosing regimens
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  • All 2 brand names
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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Reviewer: MedNext Clinical Team

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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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