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👤 Adult👶 Paediatric

Zidovudine

24 known interactions (2 severe)
2 brand names

Indications

  • HIV infection in combination with other antiretroviral drugs
  • Prevention of maternal-fetal HIV transmission
  • HIV infection in combination with other antiretroviral drugs in patients temporarily unable to take zidovudine by mouth

Drug Interactions

2 SevereModerate interactionsMinor interactions

24 drug interactions identified for Zidovudine. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Elderly; lactic acidosis; risk of haematological toxicity particularly with high dose and advanced disease; vitamin B 12 deficiency (increased risk of neutropenia) Cautions, further information Lactic...

Side Effects

nucleoside reverse transcriptase inhibitors Common or very common Abdominal pain; anaemia (may require transfusion); asthenia; diarrhoea; dizziness; fever; flatulence; headache; insomnia; nausea; neut...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Zidovir(IN)Retrovir(IN, PK, SA, AE, EG, ZA, NG)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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