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👤 Adult👶 Paediatric

Valproic Acid

41 known interactions (3 severe)
2 brand names

Indications

  • Treatment of manic episodes associated with bipolar disorder
  • Migraine prophylaxis
  • Epilepsy

Drug Interactions

3 SevereModerate interactions

41 drug interactions identified for Valproic Acid. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

acid Systemic lupus erythematosus Cautions, further information Liver toxicity Liver dysfunction (including fatal hepatic failure) has occurred in association with valproate (especially in children un...

Side Effects

acid Common or very common Abdominal pain; agitation; alopecia; anaemia; behaviour abnormal; concentration impaired; confusion; diarrhoea; drowsiness; haemorrhage; hallucination; headache; hearing los...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Depakene(IN)Convulex(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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