Trimethoprim
Indications
- Respiratory-tract infections
- Treatment of mild to moderatePneumocystis jirovecii(Pneumocystis carinii) pneumonia in patients who cannot tolerate co-trimoxazole (in combination with dapsone)
- Acne resistant to other antibacterials
- Shigellosis, Invasive salmonella infection
- Acute diverticulitis [in combination with metronidazole]
+ 7 more indications in the full monograph
Drug Interactions
25 drug interactions identified for Trimethoprim. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.
Check Interactions in AppSafety Information
Cautions
Acute porphyrias ; elderly (in adults); predisposition to folate deficiency...
Side Effects
Common or very common Diarrhoea; electrolyte imbalance; fungal overgrowth; headache; nausea; skin reactions; vomiting Rare or very rare Agranulocytosis; angioedema; anxiety; appetite decreased; arthra...
Full safety information, contraindications, and dosing available in the MedNext app.
Brand Names
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Source: MedNext Audited Proprietary Dataset
Last reviewed: 2026
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.
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