MedNext AcademyMedNext
👤 Adult👶 Paediatric

Trihexyphenidyl Hydrochloride

6 known interactions
3 brand names

Indications

  • Parkinson's disease (if used in combination with co-careldopa or co-beneldopa)
  • Parkinsonism, Drug-induced extrapyramidal symptoms (but not tardive dyskinesia)

Drug Interactions

Moderate interactions

6 drug interactions identified for Trihexyphenidyl Hydrochloride. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

Check Interactions in App

Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

hydrochloride Cardiovascular disease; elderly; gastro-intestinal obstruction; hypertension; liable to abuse; prostatic hypertrophy; psychotic disorders; pyrexia; those susceptible to angle-closure gla...

Side Effects

hydrochloride Frequency not known Anxiety; bronchial secretion decreased; confusion; constipation; delusions; dizziness; dry mouth; dysphagia; euphoric mood; fever; flushing; hallucination; insomnia; ...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Pacitane(IN)Parkin(IN)+ 1 more in app
Mn

Get the Full Monograph

Complete dosing, interactions, contraindications, side effects, and more for Trihexyphenidyl Hydrochloride.

Download Free — 7-Day Trial

No credit card required

AES-256 EncryptedNo Patient Data

In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 3 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

Access all 2866 drugs in the MedNext app

Complete monographs, AI-powered search, interaction checker, dosing calculators, and CME tracking — in 40 languages.

Download MedNext — Free 7-Day Trial