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👤 Adult

Trazodone Hydrochloride

30 known interactions (2 severe)
3 brand names

Indications

  • Depressive illness (particularly where sedation is required)
  • Anxiety

Drug Interactions

2 SevereModerate interactionsMinor interactions

30 drug interactions identified for Trazodone Hydrochloride. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

hydrochloride Arrhythmias; cardiovascular disease; chronic constipation; epilepsy; history of bipolar disorder; history of psychosis; hyperthyroidism (risk of arrhythmias); increased intra-ocular pres...

Side Effects

hydrochloride Frequency not known Aggression; agranulocytosis; alertness decreased; anaemia; anxiety; aphasia; appetite abnormal; arrhythmias; arthralgia; asthenia; blood disorder; chest pain; confusi...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Trazodone(IN)Desyrel(IN, PK, SA, AE, EG, NG)+ 1 more in app
Mn

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In the MedNext App

  • Complete dosing regimens
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  • All 3 brand names
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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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