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👤 Adult👶 Paediatric

Tofacitinib

2 known interactions (1 severe)
1 brand name

Indications

  • Moderate to severe rheumatoid arthritis (specialist use only), Psoriatic arthritis (specialist use only)
  • Moderate to severe ulcerative colitis (specialist use only)
  • Ankylosing spondylitis (specialist use only)

Drug Interactions

1 SevereModerate interactions

2 drug interactions identified for Tofacitinib. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Elderly (65 years and older); history of atherosclerotic cardiovascular disease or other cardiovascular risk factors; known risk factors for fractures; patients at risk of gastro-intestinal perforatio...

Side Effects

Common or very common Abdominal pain (more common in patients with juvenile idiopathic arthritis); anaemia; cough (more common in patients with juvenile idiopathic arthritis); diarrhoea; dyspepsia; fa...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Xeljanz(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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