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👤 Adult👶 Paediatric

Sirolimus

44 known interactions (7 severe)
2 brand names

Indications

  • Prophylaxis of organ rejection in kidney allograft recipients
  • Facial angiofibroma associated with tuberous sclerosis complex

Drug Interactions

7 SevereModerate interactionsMinor interactions

44 drug interactions identified for Sirolimus. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫁Hepatic impairment guidance

Cautions

General cautions: Hyperlipidaemia; increased susceptibility to lymphoma and other malignancies, particularly of the skin (limit exposure to UV light) Specific cautions: With oral use Increased suscept...

Side Effects

General side-effects: Common or very common Increased risk of infection; skin reactions; stomatitis Specific side-effects: Common or very common With oral use Abdominal pain; anaemia; arthralgia; asci...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Rapamune(IN, PK, SA, AE, EG, ZA, NG)Sirolimus(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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