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👤 Adult👶 Paediatric

Setmelanotide

1 known interaction
1 brand name

Indications

  • Obesity with underlying genetic aetiology [pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or leptin receptor (LEPR) deficiency] (under expert supervision)
  • Obesity with underlying genetic aetiology [Bardet-Biedl syndrome (BBS)] (under expert supervision)

Drug Interactions

Moderate interactions

1 drug interaction identified for Setmelanotide. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Contains benzyl alcohol as an excipient (risk of allergic reactions, and of metabolic acidosis due to accumulation over time)...

Side Effects

Common or very common Alopecia; asthenia; constipation; depression; diarrhoea; dizziness; dry mouth; gastrointestinal discomfort; headaches; hot flush; hyperhidrosis; muscle complaints; nausea; neopla...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Imcivree(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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