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👤 Adult👶 Paediatric

Semaglutide

16 known interactions
2 brand names

Indications

  • Type 2 diabetes mellitus as monotherapy (if metformin inappropriate), or in combination with other antidiabetic drugs (including insulin) if existing treatment fails to achieve adequate glycaemic control
  • Weight management [in conjunction with dietary measures and increased physical activity in individuals with a BMI of 30 kg/m2or more, or in individuals with a BMI of 27 kg/m2or more in the presence of at least one weight-related co-morbidity], Cardiovascular risk reduction [in conjunction with dietary measures and increased physical activity in individuals with established cardiovascular disease and a BMI of 27 kg/m2or more]

Drug Interactions

Moderate interactions

16 drug interactions identified for Semaglutide. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Diabetic retinopathy (in patients treated with insulin); general anaesthesia or deep sedation (risk of pulmonary aspiration due to delayed gastric emptying); history of pancreatitis; severe congestive...

Side Effects

General side-effects: Common or very common Appetite decreased (in patients with type 2 diabetes); burping; cholelithiasis; constipation; diarrhoea; fatigue; gastrointestinal discomfort; gastrointesti...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Ozempic(IN, PK, SA, AE, EG, ZA, NG)Rybelsus(IN)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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