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👤 Adult👶 Paediatric

Sacubitril With Valsartan

1 brand name

Indications

  • Symptomatic chronic heart failure with reduced ejection fraction [in patients not currently taking an ACE inhibitor or angiotensin II receptor antagonist, or stabilised on low doses of either of these agents]
  • Symptomatic chronic heart failure with reduced ejection fraction [in patients currently stabilised on an ACE inhibitor or angiotensin II receptor antagonist]

Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

with valsartan Serum-potassium concentration above 5.4 mmol/litre (do not initiate—may increase risk of hyperkalaemia); systolic BP less than 100 mmHg (do not initiate—limited data available)...

Side Effects

with valsartan Common or very common Anaemia; asthenia; cough; diarrhoea; dizziness; electrolyte imbalance; gastritis; headache; hypoglycaemia; hypotension; nausea; renal impairment; syncope; vertigo ...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Entresto(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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