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👤 Adult👶 Paediatric

Ruxolitinib

7 known interactions
2 brand names

Indications

  • Disease-related splenomegaly or symptoms [in patients with primary myelofibrosis, post-polycythaemia vera myelofibrosis, or post-essential thrombocythaemia myelofibrosis] (specialist use only), Polycythaemia vera (specialist use only)
  • Graft-versus-host disease [with inadequate response to corticosteroids] (under expert supervision)

Drug Interactions

Moderate interactions

7 drug interactions identified for Ruxolitinib. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Major adverse cardiovascular events; thromboembolic events (history of, or risk factors for) Cautions, further information Major adverse cardiovascular events The benefits versus risks of treatment sh...

Side Effects

Common or very common Anaemia; BK virus infection; bruising; constipation; dizziness; dyslipidaemia; flatulence; haemorrhage; headache; hypertension; increased risk of infection; intracranial haemorrh...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Jakavi(IN, PK, SA, AE, EG, ZA, NG)Jakafi(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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