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👤 Adult👶 Paediatric

Rivaroxaban

32 known interactions (6 severe)
1 brand name

Indications

  • Prophylaxis of venous thromboembolism following knee replacement surgery
  • Prophylaxis of venous thromboembolism following hip replacement surgery
  • Treatment of deep-vein thrombosis, Treatment of pulmonary embolism
  • Prophylaxis of recurrent deep-vein thrombosis, Prophylaxis of recurrent pulmonary embolism
  • Prophylaxis of stroke and systemic embolism in patients with non-valvular atrial fibrillation and with at least one of the following risk factors: congestive heart failure, hypertension, previous stroke or transient ischaemic attack, age ≥ 75 years, or diabetes mellitus

+ 2 more indications in the full monograph

Drug Interactions

6 SevereModerate interactionsMinor interactions

32 drug interactions identified for Rivaroxaban. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

General cautions: Anaesthesia with postoperative indwelling epidural catheter (risk of paralysis—monitor neurological signs and wait at least 18 hours after rivaroxaban dose before removing catheter a...

Side Effects

Common or very common Anaemia; asthenia; constipation; diarrhoea; dizziness; fever; gastrointestinal discomfort; haemorrhage; headache; hypotension; menorrhagia; nausea; oedema; pain in extremity; pos...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Xarelto(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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