MedNext AcademyMedNext
👤 Adult

Riociguat

38 known interactions (1 severe)
1 brand name

Indications

  • Chronic thromboembolic pulmonary hypertension that is recurrent or persistent following surgery, or is inoperable (initiated under specialist supervision), Monotherapy or in combination with an endothelin receptor antagonist

Drug Interactions

1 SevereModerate interactionsMinor interactions

38 drug interactions identified for Riociguat. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

Check Interactions in App

Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Autonomic dysfunction; elderly (risk of hypotension); hypotension (do not initiate if systolic blood pressure below 95 mmHg); hypovolaemia; severe left ventricular outflow obstruction Cautions, furthe...

Side Effects

Common or very common Anaemia; constipation; diarrhoea; dizziness; dysphagia; gastroenteritis; gastrointestinal discomfort; gastrointestinal disorders; haemorrhage; headache; hypotension; nasal conges...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Adempas(IN, PK, SA, AE, EG, ZA, NG)
Mn

Get the Full Monograph

Complete dosing, interactions, contraindications, side effects, and more for Riociguat.

Download Free — 7-Day Trial

No credit card required

AES-256 EncryptedNo Patient Data

In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 1 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

Access all 2866 drugs in the MedNext app

Complete monographs, AI-powered search, interaction checker, dosing calculators, and CME tracking — in 40 languages.

Download MedNext — Free 7-Day Trial