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👤 Adult👶 Paediatric

Rilpivirine

45 known interactions (1 severe)
1 brand name

Indications

  • HIV-1 infection [in combination with other antiretroviral drugs] (specialist use only)
  • HIV-1 infection [oral lead-in therapy, in combination with cabotegravir] (specialist use only)
  • HIV-1 infection [in combination with cabotegravir prolonged-release injection] (specialist use only)

Drug Interactions

1 SevereModerate interactionsMinor interactions

45 drug interactions identified for Rilpivirine. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Acute porphyrias ; co-infection with hepatitis B or C; risk factors for virological failure Cautions, further information Risk factors for virological failure Use with caution in patients with HIV-1 s...

Side Effects

General side-effects: Common or very common Depression; dizziness; drowsiness; gastrointestinal discomfort; headache; nausea; sleep disorders; vomiting Specific side-effects: Common or very common Wit...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Edurant(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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