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👤 Adult👶 Paediatric

Rifampicin

32 known interactions (1 severe)
3 brand names

Indications

  • Brucellosis in combination with other antibacterials, Legionnaires disease in combination with other antibacterials, Serious staphylococcal infections in combination with other antibacterials
  • Endocarditis in combination with other drugs
  • Tuberculosis, in combination with other drugs (intermittent supervised 6-month treatment) (under expert supervision)
  • Tuberculosis, in combination with other drugs (standard unsupervised 6-month treatment)
  • Prevention of tuberculosis in susceptible close contacts or those who have become tuberculin positive, in combination with isoniazid

+ 5 more indications in the full monograph

Drug Interactions

1 SevereModerate interactions

32 drug interactions identified for Rifampicin. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Discolours soft contact lenses...

Side Effects

General side-effects: Common or very common Nausea; thrombocytopenia; vomiting Uncommon Diarrhoea; leucopenia Frequency not known Abdominal discomfort; acute kidney injury; adrenal insufficiency; agra...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Rifadin(IN, PK, SA, AE, EG, ZA, NG)R-Cinex(IN, IN)+ 1 more in app
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 3 brand names
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  • CME/CPD tracking
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  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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