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👤 Adult👶 Paediatric

Propofol

6 known interactions
2 brand names

Indications

  • Induction of anaesthesia using 0.5% or 1% injection
  • Induction of anaesthesia using 2% injection
  • Maintenance of anaesthesia using 1% injection
  • Maintenance of anaesthesia using 2% injection
  • Sedation of ventilated patients in intensive care using 1% or 2% injection

+ 2 more indications in the full monograph

Drug Interactions

Moderate interactions

6 drug interactions identified for Propofol. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Acute circulatory failure (shock); cardiac impairment; cardiovascular disease; elderly; epilepsy; fixed cardiac output; hypotension; hypovolaemia; raised intracranial pressure; respiratory impairment...

Side Effects

Common or very common Apnoea; arrhythmias; headache; hypotension; localised pain; nausea; vomiting Uncommon Thrombosis Rare or very rare Epileptiform seizure (may be delayed); movement disorders; panc...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Diprivan(IN, PK, SA, AE, EG, ZA, NG)Propofol(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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