👤 Adult

Progesterone

10 known interactions (2 severe)

2 brand names

Indications

Supplementation of luteal phase in infertility (under expert supervision)
Adjunct in in-vitro fertilisation [when mainly tubal, idiopathic, or endometriosis related infertility is associated with normal ovulatory cycles] (under expert supervision)
Premenstrual syndrome, Post-natal depression
Supplementation of luteal phase during assisted reproductive technology (ART) treatment (under expert supervision)
Threatened miscarriage [with vaginal bleeding and previous miscarriage] (initiated by a specialist)

+ 4 more indications in the full monograph

Drug Interactions

2 SevereModerate interactions

10 drug interactions identified for Progesterone. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available

🤱Breastfeeding guidance available

🫘Renal impairment guidance

🫁Hepatic impairment guidance

⚠️Requires renal dose adjustment

Cautions

Conditions that may worsen with fluid retention; diabetes (progestogens can decrease glucose tolerance—monitor patient closely); history of depression; migraine; risk factors for thromboembolism...

Side Effects

Common or very common With oral use Headache; menstrual cycle irregularities With vaginal use Breast pain; drowsiness; gastrointestinal discomfort Uncommon With oral use Breast pain; constipation; dia...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Utrogestan(IN, PK, SA, AE, EG, ZA, NG)Susten(IN)

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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