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👤 Adult👶 Paediatric

Phytomenadione

1 known interaction (1 severe)
2 brand names

Indications

  • Major bleeding in patients on warfarin (in combination with dried prothrombin complex or fresh frozen plasma)
  • INR > 8.0 with minor bleeding in patients on warfarin
  • INR > 8.0 with no bleeding in patients on warfarin
  • INR 5.0–8.0 with minor bleeding in patients on warfarin
  • Reversal of anticoagulation prior to elective surgery (after warfarin stopped)

+ 1 more indication in the full monograph

Drug Interactions

1 Severe

1 drug interaction identified for Phytomenadione. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫁Hepatic impairment guidance

Cautions

Intravenous injections should be given very slowly—reports of anaphylactoid reactions Cautions For Konakion® MM Reduce dose in elderly...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Konakion(IN, PK, SA, AE, EG, ZA, NG)Vitamin K1(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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