👶 Paediatric🔒 Controlled

Phenobarbital

Unknown

350 known interactions (16 severe)

2 brand names

Indications

All forms of epilepsy except typical absence seizures for phenobarbital
Status epilepticus for phenobarbital

Drug Interactions

16 SevereModerate interactionsMinor interactions

350 drug interactions identified for Phenobarbital. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available

🤱Breastfeeding guidance available

🫘Renal impairment guidance

🫁Hepatic impairment guidance

⚠️Requires renal dose adjustment

Cautions

Avoid in Acute porphyrias ; children; debilitated; history of alcohol abuse; history of drug abuse; respiratory depression (avoid if severe); seizures (may be exacerbated) Cautions, further informatio...

Side Effects

General side-effects: Frequency not known Agitation; agranulocytosis; anticonvulsant hypersensitivity syndrome; behaviour abnormal; bone disorders; bone fracture; cognitive impairment; confusion; depr...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Gardenal(IN, IN, IN)Luminal(IN, PK, SA, AE, EG, ZA, NG, IN, PK, SA, AE, EG, ZA, NG, IN, PK, SA, AE, EG, ZA, NG)

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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