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👤 Adult👶 Paediatric

Naloxone Hydrochloride

7 known interactions
2 brand names

Indications

  • Acute opioid overdose–high-dose regimen [when rapid titration with naloxone is necessary to reverse potentially life-threatening effects]
  • Opioid overdose–low-dose regimen [when there is risk of acute withdrawal, or when a continued therapeutic effect is required (e.g. postoperative use, palliative care)]
  • Opioid overdose in non-medical and medical settings
  • Opioid overdose in non-medical and medical settings [in opioid-dependent patients when there is risk of acute withdrawal]
  • Opioid overdose in a non-medical setting

Drug Interactions

Moderate interactions

7 drug interactions identified for Naloxone Hydrochloride. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available

Cautions

hydrochloride Cardiovascular disease or those receiving cardiotoxic drugs (serious adverse cardiovascular effects reported); chronic opioid use (risk of acute withdrawal); maternal chronic opioid use ...

Side Effects

hydrochloride General side-effects: Common or very common Arrhythmias; dizziness; headache; hypertension; hypotension; nausea; vomiting Uncommon Diarrhoea; dry mouth; hyperhidrosis; hyperventilation; ...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Narcan(IN, PK, SA, AE, EG, ZA, NG)Naloxone(IN)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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