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Mifepristone

7 known interactions
2 brand names

Indications

  • Cervical ripening before mechanical cervical dilatation
  • Induction of labour in intra-uterine fetal death in women without uterine scarring (under close medical supervision)
  • Medical termination of intra-uterine pregnancy of up to 49 days gestation (under close medical supervision)
  • Medical termination of intra-uterine pregnancy of 50–63 days gestation (under close medical supervision)
  • Termination of pregnancy of 13–24 weeks gestation (in combination with a prostaglandin) (under close medical supervision)

+ 1 more indication in the full monograph

Drug Interactions

Moderate interactions

7 drug interactions identified for Mifepristone. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Adrenal suppression (may require corticosteroid); anticoagulant therapy; asthma (avoid if severe and uncontrolled); existing cardiovascular disease; haemorrhagic disorders; history of endocarditis; pr...

Side Effects

Common or very common Abdominal cramps; diarrhoea; infection; nausea; pelvic inflammatory disease; uterine disorders; vaginal haemorrhage (sometimes severe); vomiting Uncommon Hypotension Rare or very...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Mifepristone(IN)Mifegyne(IN, PK, SA, AE, EG, ZA, NG, PK, SA, AE, EG, ZA, NG)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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