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👤 Adult👶 Paediatric

Metyrapone

5 known interactions
1 brand name

Indications

  • Differential diagnosis of ACTH-dependent Cushing's syndrome (specialist supervision in hospital)
  • Management of Cushing's syndrome (specialist supervision in hospital)
  • Resistant oedema due to increased aldosterone secretion in cirrhosis, nephrotic syndrome, and congestive heart failure (with glucocorticoid replacement therapy) (specialist supervision in hospital)

Drug Interactions

Moderate interactions

5 drug interactions identified for Metyrapone. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫁Hepatic impairment guidance

Cautions

Avoid in Acute porphyrias ; gross hypopituitarism (risk of precipitating acute adrenal failure); hypertension on long-term administration; hypothyroidism (delayed response)...

Side Effects

Common or very common Dizziness; headache; hypotension; nausea; sedation; vomiting Rare or very rare Abdominal pain; adrenal insufficiency; allergic dermatitis; hirsutism Frequency not known Alopecia;...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Metopirone(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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