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👤 Adult👶 Paediatric

Methylprednisolone

31 known interactions
2 brand names

Indications

  • Suppression of inflammatory and allergic disorders, Cerebral oedema associated with malignancy
  • Treatment of graft rejection reactions
  • Treatment of relapse in multiple sclerosis
  • Treatment of relapse in multiple sclerosis (when oral steroids have failed or have not been tolerated, or in those who require hospital admission)
  • Local inflammation of joints and soft tissues

+ 1 more indication in the full monograph

Drug Interactions

Moderate interactions

31 drug interactions identified for Methylprednisolone. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

corticosteroids (systemic) Congestive heart failure; diabetes mellitus (including a family history of); diverticular disease (increased risk of diverticular perforation); diverticulitis; epilepsy; gla...

Side Effects

corticosteroids (systemic) Common or very common Anxiety; appetite increased; behaviour abnormal; cataract subcapsular; cognitive impairment; Cushing's syndrome; electrolyte imbalance; fluid retention...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Medrol(IN, PK, SA, AE, EG, ZA, NG)Solu-Medrol(IN, PK)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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