Mercaptopurine
Indications
- Severe acute Crohn's disease (under expert supervision), Maintenance of remission of Crohn's disease (under expert supervision), Maintenance of remission of ulcerative colitis (under expert supervision)
- Acute leukaemias (specialist use only), Chronic myeloid leukaemia (specialist use only)
Drug Interactions
21 drug interactions identified for Mercaptopurine. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.
Check Interactions in AppSafety Information
Cautions
Reduced thiopurine methyltransferase activity Cautions, further information Thiopurine methyltransferase The enzyme thiopurine methyltransferase (TPMT) metabolises thiopurine drugs (azathioprine, merc...
Side Effects
Common or very common Anaemia; appetite decreased; bone marrow depression; diarrhoea; hepatic disorders; hepatotoxicity (more common at high doses); leucopenia; nausea; oral disorders; pancreatitis; t...
Full safety information, contraindications, and dosing available in the MedNext app.
Brand Names
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Source: MedNext Audited Proprietary Dataset
Last reviewed: 2026
Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.
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