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Medroxyprogesterone Acetate

6 known interactions (1 severe)
2 brand names

Indications

  • Dysfunctional uterine bleeding
  • Secondary amenorrhoea
  • Mild to moderate endometriosis
  • Progestogenic opposition of oestrogen HRT
  • Endometrial cancer, Renal cell cancer

+ 5 more indications in the full monograph

Drug Interactions

1 SevereModerate interactions

6 drug interactions identified for Medroxyprogesterone Acetate. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

acetate General cautions: Cardiac dysfunction; conditions that may worsen with fluid retention; diabetes (progestogens can decrease glucose tolerance—monitor patient closely); history of breast cancer...

Side Effects

acetate General side-effects: Common or very common Alopecia; breast abnormalities; depression; dizziness; fluid retention; insomnia; menstrual cycle irregularities; nausea; sexual dysfunction; skin r...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Provera(IN, PK, SA, AE, EG, ZA, NG)Meprate(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 2 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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