👤 Adult

Macitentan

27 known interactions

1 brand name

Indications

Pulmonary arterial hypertension (initiated under specialist supervision)

Drug Interactions

Moderate interactions

27 drug interactions identified for Macitentan. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available

🤱Breastfeeding guidance available

🫘Renal impairment guidance

🫁Hepatic impairment guidance

⚠️Requires renal dose adjustment

Cautions

Patients over 75 years; pulmonary veno-occlusive disease...

Side Effects

Common or very common Anaemia; fluid retention; flushing; headache; hypotension; increased risk of infection; leucopenia; nasal congestion; oedema; thrombocytopenia...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Opsumit(IN, PK, SA, AE, EG, ZA, NG)

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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