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👤 Adult👶 Paediatric

Lumacaftor With Ivacaftor

1 brand name

Indications

  • Cystic fibrosis (specialist use only)

Safety Information

🫁Hepatic impairment guidance

Cautions

with ivacaftor Forced expiratory volume in 1 second (FEV 1 ) less than 40% of the predicted normal value—additional monitoring recommended at initiation of treatment; pulmonary exacerbation—no informa...

Side Effects

with ivacaftor Common or very common Breast abnormalities; diarrhoea; dizziness; dyspnoea; ear discomfort; flatulence; gastrointestinal discomfort; headache; increased risk of infection; menstrual cyc...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Orkambi(IN, PK, SA, AE, EG, ZA, NG)
Mn

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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