MedNext AcademyMedNext
👤 Adult👶 Paediatric

Levofolinic Acid

1 brand name

Indications

  • Prevention of methotrexate-induced adverse effects
  • Suspected methotrexate overdosage
  • Adjunct to fluorouracil in colorectal cancer

Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available

Cautions

acid Avoid simultaneous administration of methotrexate; not indicated for pernicious anaemia or other megaloblastic anaemias caused by vitamin B 12 deficiency...

Side Effects

acid Common or very common Dehydration; diarrhoea; mucosal toxicity; nausea; vomiting Uncommon Fever Rare or very rare Agitation (with high doses); depression (with high doses); epilepsy exacerbated; ...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Isovorin(IN, PK, SA, AE, EG, ZA, NG)
Mn

Get the Full Monograph

Complete dosing, interactions, contraindications, side effects, and more for Levofolinic Acid.

Download Free — 7-Day Trial

No credit card required

AES-256 EncryptedNo Patient Data

In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 1 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

Access all 2866 drugs in the MedNext app

Complete monographs, AI-powered search, interaction checker, dosing calculators, and CME tracking — in 40 languages.

Download MedNext — Free 7-Day Trial