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👤 Adult

Letrozole

8 known interactions
2 brand names

Indications

  • First-line treatment in postmenopausal women with hormone-dependent advanced breast cancer, Adjuvant treatment of oestrogen-receptor-positive invasive early breast cancer in postmenopausal women, Advanced breast cancer in postmenopausal women (naturally or artificially induced menopause) in whom other anti-oestrogen therapy has failed, Extended adjuvant treatment of hormone-dependent invasive breast cancer in postmenopausal women who have received standard adjuvant tamoxifen therapy

Drug Interactions

Moderate interactions

8 drug interactions identified for Letrozole. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Susceptibility to osteoporosis...

Side Effects

Common or very common Alopecia; appetite abnormal; arthralgia; asthenia; bone fracture; bone pain; constipation; depression; diarrhoea; dizziness; gastrointestinal discomfort; headache; hot flush; hyp...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Femara(IN, PK, SA, AE, EG, ZA, NG)Letoval(IN)
Mn

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In the MedNext App

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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