MedNext AcademyMedNext
👤 Adult👶 Paediatric

Isotretinoin

2 known interactions
4 brand names

Indications

  • Severe acne [(such as nodular or conglobate acne or acne at risk of permanent scarring) resistant to adequate courses of standard therapy with systemic antibacterials and topical therapy] (under expert supervision)

Drug Interactions

Moderate interactions

2 drug interactions identified for Isotretinoin. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

Check Interactions in App

Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

Important safety information For isotretinoin MHRA/CHM advice: Isotretinoin ( Roaccutane ®): rare reports of erectile dysfunction and decreased libido (October 2017) An EU-wide review has concluded th...

Side Effects

Common or very common Anaemia; arthralgia; back pain; cheilitis; dry eye; eye discomfort; eye inflammation; haemorrhage; headache; increased risk of infection; myalgia; nasal dryness; neutropenia; pro...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Isotroin(IN)Tretiva(IN)+ 2 more in app
Mn

Get the Full Monograph

Complete dosing, interactions, contraindications, side effects, and more for Isotretinoin.

Download Free — 7-Day Trial

No credit card required

AES-256 EncryptedNo Patient Data

In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
  • AI-powered drug search
  • All 4 brand names
  • Dosing calculators
  • CME/CPD tracking
  • 40 language support
  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

Access all 2866 drugs in the MedNext app

Complete monographs, AI-powered search, interaction checker, dosing calculators, and CME tracking — in 40 languages.

Download MedNext — Free 7-Day Trial