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👤 Adult👶 Paediatric

Hydrocortisone

2 known interactions
3 brand names

Indications

  • Thyrotoxic crisis [thyroid storm]
  • Adrenocortical insufficiency resulting from septic shock
  • Acute hypersensitivity reactions such as angioedema of the upper respiratory tract and anaphylaxis [adjunct to adrenaline]
  • Corticosteroid replacement [patients who have taken more than 10 mg prednisolone per day or equivalent within 3 months of minor surgery under general anaesthesia]
  • Corticosteroid replacement [patients who have taken more than 10 mg prednisolone per day or equivalent within 3 months of moderate or major surgery]

+ 16 more indications in the full monograph

Drug Interactions

Moderate interactions

2 drug interactions identified for Hydrocortisone. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

corticosteroids (systemic) Congestive heart failure; diabetes mellitus (including a family history of); diverticular disease (increased risk of diverticular perforation); diverticulitis; epilepsy; gla...

Side Effects

corticosteroids (systemic) Common or very common Anxiety; appetite increased; behaviour abnormal; cataract subcapsular; cognitive impairment; Cushing's syndrome; electrolyte imbalance; fluid retention...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Hydrocortisone(IN, NG)Efcorlin(IN)+ 1 more in app
Mn

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In the MedNext App

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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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