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👤 Adult👶 Paediatric

Hydralazine Hydrochloride

6 known interactions
2 brand names

Indications

  • Moderate to severe hypertension (adjunct)
  • Heart failure (with long acting nitrate) (initiated in hospital or under specialist supervision)
  • Hypertensive emergencies (including during pregnancy), Hypertension with renal complications

Drug Interactions

Moderate interactions

6 drug interactions identified for Hydralazine Hydrochloride. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

hydrochloride Cerebrovascular disease; coronary artery disease (may provoke angina, avoid after myocardial infarction until stabilised); occasionally blood pressure reduction too rapid even with low p...

Side Effects

hydrochloride Common or very common Angina pectoris; diarrhoea; dizziness; flushing; gastrointestinal disorders; headache; hypotension; joint disorders; lupus-like syndrome (after long-term therapy wi...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Nepresol(IN)Apresoline(PK, SA, AE, EG, ZA, NG)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 2 brand names
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  • CME/CPD tracking
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Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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