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Folinic Acid

2 known interactions
2 brand names

Indications

  • Prevention of methotrexate-induced adverse effects
  • Suspected methotrexate overdosage
  • Adjunct to fluorouracil in colorectal cancer
  • As an antidote to methotrexate

Drug Interactions

Moderate interactions

2 drug interactions identified for Folinic Acid. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available

Cautions

acid Avoid simultaneous administration of methotrexate; not indicated for pernicious anaemia or other megaloblastic anaemias caused by vitamin B 12 deficiency...

Side Effects

acid Common or very common With intravenous use Bone marrow failure; dehydration; diarrhoea; mucositis; nausea; oral disorders; skin reactions; vomiting Uncommon With intramuscular use Fever With intr...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Leucovorin(IN, PK, SA, AE, EG, ZA, NG)Folinext(IN)
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 2 brand names
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  • CME/CPD tracking
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  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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