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👤 Adult👶 Paediatric

Esomeprazole

62 known interactions (2 severe)
3 brand names

Indications

  • Peptic ulcer disease
  • NSAID-associated gastric ulcer
  • Prophylaxis of NSAID-associated gastric ulcer in patients with an increased risk of gastroduodenal complications who require continued NSAID treatment
  • Prophylaxis of NSAID-associated gastric or duodenal ulcer
  • Gastro-oesophageal reflux disease (in the presence of erosive reflux oesophagitis)

+ 7 more indications in the full monograph

Drug Interactions

2 SevereModerate interactionsMinor interactions

62 drug interactions identified for Esomeprazole. Check the full interaction details, severity ratings, and clinical recommendations in the MedNext app.

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Safety Information

🤰Pregnancy guidance available
🤱Breastfeeding guidance available
🫘Renal impairment guidance
🫁Hepatic impairment guidance
⚠️Requires renal dose adjustment

Cautions

proton pump inhibitors Can increase the risk of fractures (particularly when used at high doses for over a year in the elderly) (in adults); may increase the risk of gastro-intestinal infections (incl...

Side Effects

proton pump inhibitors Common or very common Abdominal pain; constipation; diarrhoea; dizziness; dry mouth; gastrointestinal disorders; headache; insomnia; nausea; skin reactions; vomiting Uncommon Ar...

Full safety information, contraindications, and dosing available in the MedNext app.

Brand Names

Nexpro(IN)Nexium(IN, PK, SA, AE, EG, ZA, NG)+ 1 more in app
Mn

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In the MedNext App

  • Complete dosing regimens
  • Full interaction details & severity
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  • All 3 brand names
  • Dosing calculators
  • CME/CPD tracking
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  • Offline access

Source: MedNext Audited Proprietary Dataset

Last reviewed: 2026

Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice. Always consult a qualified healthcare professional before making clinical decisions. Verify all drug information with current clinical guidelines.

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